Biliary Atresia
Conditions
Interventions
group 1:Given Yinzhihuang with Ligustrazine from the day 3 after operation
group 2:Given Yinzhihuang with placebo from the day 3
group A:Divide two groups according different glucocorticoid, group A is given dexamethasone from the seventh day after operation
group B:Divide two groups according different glucocorticoid, group B is given methylprednisolone from the seventh day after operation
Sponsors
The First Affiliated Hospital of Sun Yat Sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patient be diagnosd as biliary atresia and has underwent Kasai procedure; 2. The bile drainage is well postoperation; 3. The age is less than 90 days; 4. Informed consents and willing to participant; signed the informed consent form accords with ethics principles.
Exclusion criteria
Exclusion criteria: 1. The patient has little bile drainage postoperation; 2. Patient cannot tolerate the therapy for all reasons; 3. The patient and their family reject to participart the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the color of faeces, skin of forehead and sclera;the size, hardness, edge of liver and the size of spleen; the evidence of portal hypertension;The degree of liver fibrosis;total bilirubin, direct bilirubin, the ratio of direct bilirubin to indirect bilirubin; | — |
Countries
China
Contacts
Public ContactLiu Juncheng
Outcome results
None listed