Breast cancer
Conditions
Interventions
ESM group:Endoscopic subcutaneous mastectomy with axillary l
BCS group:Breast conserving surgery
Sponsors
Southwest Hospital, Third Military Medical University
Eligibility
Sex/Gender
Female
Age
No minimum to 55 Years
Inclusion criteria
Inclusion criteria: female; age <55 years; invasive breast cancer confirmed histopathologically by preoperative core needle biopsy or excision biopsy; the largest tumor diameter smaller than 3 cm primarily or after neoadjuvant chemotherapy; no deviation or retraction of nipple; no obviously enlarged or fused axillary lymph nodes; no distant metastasis found by auxiliary examination; consent of neoadjuvant chemotherapy with TE regimen (taxol 175 mg/m2, epirubicin 80 mg/m2, IV day 1; cycled every 21 days for 1-4 cycles).
Exclusion criteria
Exclusion criteria: age >55 years; with deviation or retraction of nipple; with obviously enlarged or fused axillary lymph nodes; with distant metastasis found by auxiliary examination; rejection of neoadjuvant chemotherapy with TE regimen (taxol 175 mg/m2, epirubicin 80 mg/m2, IV day 1; cycled every 21 days for 1-4 cycles); the largest tumor diameter larger than 3 cm primarily or after neoadjuvant chemotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease-free survival rate;Total survival rate;Postoperative cosmetic satisfaction rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complication rate; | — |
Countries
China
Contacts
Public ContactLinjun FAN
Outcome results
None listed