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Long-term effect of prophylactic laser treatment for bilateral soft drusen

Long-term effect of prophylactic laser treatment for bilateral soft drusen

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TNRC-08000221
Enrollment
Unknown
Registered
2008-11-12
Start date
1999-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

age-related maculopathy, drusen

Interventions

The treatment group:an argon green laser(514nM) Approximately 100 laser spots of 0.1 seconds duration and 200um spot size to produce a barely visible lesion(55-100mW)(subthreshold intensity
the control group:The contralateral eye of the patients no laser treatment

Sponsors

Beijing Friendship Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Each eye had more than 10 soft drusen (>125 microm). The both eyes of the best corrected visual acuity (BCVA) were 0.8 or better. The Fluorescein angiography test showed no choroidal neovascularization (CNV) and geographic atrophy.

Exclusion criteria

Exclusion criteria: The Patients with exudative macular degeneration in either eye, macular or retinal diseases that would interfere with vision such as central serous choroidopathy, optic atrophy, macular pucker, macular hole, retinal vascular disease such as diabetic retinopathy and retinal vein occlusion, active uveitis, other sight-threatening retinopathies, or other retinal degeneration in either eye were excluded.

Design outcomes

Primary

MeasureTime frame
the best corrected visual acuity (BCVA);drusen numbe;

Secondary

MeasureTime frame
function of macula;function of macula;Light sensitivit;

Countries

China

Contacts

Public ContactHuang Ying-xiang
bshuang@163.com+86 13466652235

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026