Chronic atrophic gastritis
Conditions
Interventions
Celecoxib group:Celecoxib 200mg, bid, x3m
Combine group:Celecoxib 200mg, bid, x3m, Amoxicillin 500mg, bid, x1w
Klaricid 500mg, bid, x1w
Nexium 40mg, qd, x1w
Anti-HP group:Amoxicillin 500mg, bid, x1w
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
No minimum to 65 Years
Inclusion criteria
Inclusion criteria: 1. Age<65; 2. Chronic atrophic gastritis diagnosed by upper gastrointestinal endoscopy and histology test once before or for the first time in our hospital; 3. Willing to take the follow-up investigation, sign informed consent documents; 4. Normal client with tolerable digestive symptom, without problem through brief physical examination; 5. Normal digestive test results like enteroscopy, ultrasound, capsule endoscopy, et al; 6. Without diabetes, disease and dysfunction in cardiovascular, respiratory, urinary, nervous system and systemic inflammatory, in a stressless condition.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or lactating mother; 2. Active peptic ulcer; 3. Previous gastrectomy; 4. Suspected or confirmed cancer(gastric cancer included); 5. Allergy to prescribed medication; 6. Concomitant use of other antibiotics, proton pump inhibitors, H2 receptor antagonists or non-steroidal anti-inflammatory drugs over last 4weeks; 7. Can not stand endoscopy; 8. Cardiovascular and cerebrovascular disease; 9. Abnormal in biochemistry test.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biochemical indicator;Histological indicato; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life; | — |
Countries
China
Contacts
Public ContactTang cheng-wei
Outcome results
None listed