volunteers
Conditions
Interventions
300ug group:orally administered recombinant hGM-CSF
600ug group:orally administered recombinant hGM-CSF
120ug group:orally administered recombinant hGM-CSF
900ug group:orally administered recombinant hGM-CSF
720ug group:orally administered recombinant hGM-CSF
240 ug(twice daily) group:orally administered recombinant hGM-CSF(twice dail)
120ug(twice daily) group:orally administered recombinant hGM-CSF(twice dail)
Sponsors
Second Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
Male
Age
20 Years to 30 Years
Inclusion criteria
Inclusion criteria: Male and female healthy volunteers, aged 20 to 30 years old and weigh at 45 ~ 75 kg within the past subjects are unmotivated, liver, kidney, gastrointestinal and metabolic disorders, neuropsychiatric diseases, such as medical history and drug allergies History, smoke-free, wine hobby, and within three months without participating in any drug test and using any other drugs. Healthy volunteers signed informed consent and were conducted a comprehensive history and physical examination and laboratory tests including blood pressure, heart rate and body temperature measurements, blood examination, urine analysis, blood biochemistry, HBAg determination and ECG, etc. Successful applicants have access to trial.
Exclusion criteria
Exclusion criteria: Pregnancy or breast-feeding women, drug allergy or a history of allergic disease; spirit of defects; bleeding family or personal history have gastrointestinal and urinary tract reproductive, cardiovascular, nervous system, liver, kidney, lung disease and metabolic history; smoke (> 10 / day) wine hobby; a history of drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safet; | — |
Countries
China
Contacts
Public ContactYaozhou Zhang
Outcome results
None listed