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L-asparaginase, cisplatin, Etoposide and Dexamethasone (LVDP) protocol in combination with radiotherapy for patinets with newly diagnosed NK/T cell lymphoma

L-asparaginase, cisplatin, Etoposide and Dexamethasone (LVDP) protocol in combination with radiotherapy for patinets with newly diagnosed NK/T cell lymphoma

Status
Active, not recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-TNC-12002353
Enrollment
Unknown
Registered
2012-05-30
Start date
2010-04-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extranodal NK/T cell lymphoma, nasal type

Interventions

phase I/II:chemotherapy and radiotherapy
stage III/IV:chemotherapy and radiotherapy

Sponsors

Department of Medical Oncology, Cancer Center, West China Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Nasal type NK/T-cell lymphoma proved by pathology and immunohistology; 2. No chemotherapy or radiation was administered since diagnosis; 3. Performance status as ECOG 0-2 and no contraindication to chemotherapy; 4. Expectation of life was over 12 weeks; 5. Voluntary participation and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating women; 2. Patients combined with any unstable systemic diseases; 3. Any conditions that the investigator regards to be not suitable for current study.

Design outcomes

Primary

MeasureTime frame
overall response rate;time to progress;one year and two year survival rate;

Secondary

MeasureTime frame
overall survival;Grade 3/4 toxicities;complete response rate;

Countries

China

Contacts

Public ContactLiqun Zou
hxlcyxy@163.com+86 18980601027

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026