A phase II trial of S-1 and concurrent radiotherapy plus S-1 chemotherapy for peri-ampullar carcinoma after radical excision

Status

Recruiting

Phases

Phase 2

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-TNC-11001362

Enrollment

Unknown

Registered

2011-06-06

Start date

2011-05-27

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

peri-ampullar carcinoma

Interventions

1:S-1 and concurrent radiotherapy + S-1 chemotherapy

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years old; 2. Able and willing to provide signed informed consent; 3. peri-ampullar carcinoma after radical excision; 4. KPS scores were >=80; 5. Hb>=110g/L, WBC>=4.0*10^9/L, Plt>=75*10^9/L; Cr<=1.0*ULN, AST and ALT<=2.0*ULN, AKP<=5*ULN.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactatingfemales; 2. Metastasis or local recurrence from peri-ampullar carcinoma; 3. Coincident other cancer; 4. Prior chemotherapy and/or radiontherapy history; 5. Severe complication such as heart disease or renal disease; 6. Bad compliance.

Design outcomes

Primary

Measure	Time frame
disease free survival(DFS);overall survival(OS);	—

Countries

China

Contacts

Public ContactWenhui Lou

lou.wenhui@zs-hospital.sh.cn+86 13681971683

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026