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Reactive myocardial fibrosis related mechanical dyssynchrony in patients with hypertension – An early marker of myocardial involvement?

Reactive myocardial fibrosis related mechanical dyssynchrony in patients with hypertension – An early marker of myocardial involvement?

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-TCS-14004477
Enrollment
Unknown
Registered
2014-04-10
Start date
2015-01-05
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

two groups:None versus N/A

Sponsors

The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with hypertension which is defined as systolic blood pressure (SBP) >=140mmHg or diastolic blood pressure (DBP) >=90mmHg or the use of antihypertensive agents.

Exclusion criteria

Exclusion criteria: Pregnancy, hypothyroidism, clinically significant renal disease (serum creatinine level >=270ìmol/l), secondary hypertension and diabetes mellitus. Those with LV ejection fraction <50% or myocarditis, evidence of clinical coronary artery or pericardial disease, coronary revascularization, bundle-branch block, second-degree or higher atrioventricular block, atrial fibrillation, or greater than mild aortic or mitral valve diseases.

Design outcomes

Primary

MeasureTime frame
Changes of fibrosis and dyssynchorny after 2 years;—

Countries

China

Contacts

Public ContactSHANG, Qing

Department of Medicine & Therapeutics, CUHK

qingshang@cuhk.edu.hk+852 2632 3840

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026