Dysglycemia (impaired glucose tolerance or type 2 diabetes)
Conditions
Interventions
Morbid obesity group:Billroth II Gastrojejunostomy
Gastric tumor group:Bariatic surgery
Sponsors
Department of Endocrinology, West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Male and female aged 18 to 70 years old; 2. Able and willing to provide signed informed consent; 3. In need of gastrointestinal surgery for different disease(A. Gastric tumor; B. Morbid Obesity: BMI>=32 or BMI>=28 complicated with metabolic disturbance); 4. Dysglycemia (impaired glucose tolerance or type 2 diabetes); 5. Normoglycaemia matched to dysglycemia in other conditions as control group; 6. Willing to accept the follow-up; 7. No smoking for 6 weeks before surgery.
Exclusion criteria
Exclusion criteria: 1. Unable to accept surgery for advanced gastric carcinoma; 2. Reject the follow-up; 3. Pregnant or lactating women; 4. Serious complications after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| oral glucose tolerance test+insulin releasing test;gastrointestinal hormone (Leptin, GLP-1, GIP, Ghrelin, PYY, Gastrin); | — |
Secondary
| Measure | Time frame |
|---|---|
| height, weight, waistline, blood pressure; | — |
Countries
China
Contacts
Public ContactHaoming Tian
Outcome results
None listed