Atherosclerosis
Conditions
Interventions
research group:Ultrasound ablation
Sponsors
Department of Ultrasound, Xijing Hospital, the Fourth Military Medical University
Eligibility
Sex/Gender
All
Age
35 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. To be aged 35 to 65 years old; 2. To be with bilateral or unilateral carotid atherosclerotic disease; 3. without carotid surgery operation, the history of interventional therapy in patients with ischemic encephalopathy; 4. ultrasound carotid artery plaque without ulcers and internal bleeding, the maximum thickness of plaque is more than 2mm, carotid artery stenosis rate of less than 50% patients; 5. no the heart, liver, kidney function was not complete; 6. patients (or guardian, lineal relatives) signed the informed consent of patients; 7. Patient who is considered to be suite for the study by the investigator.
Exclusion criteria
Exclusion criteria: 1. carotid surgery operation, the history of interventional therapy in patients with ischemic encephalopathy; 2. occurred within one year after cerebral infarction, transient ischemic attack patients; 3. occurred within one year after myocardial infarction and treated patients; 4. ipsilateral carotid artery severe tortuosity, difficult to obtain accurate measurement results; 5. patients with serious heart, liver, kidney dysfunction; 6. blood pressure higher than 180/100mmHg; 7. patients with bleeding tendency; 8. in critical condition and other condition that cannot complete carotid examination; 9. can not complete the prescribed course of protocol; 10. did not sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The maximum thickness of plaque;Percent area stenosi; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gray median;Vmax; | — |
Countries
China
Contacts
Public ContactZhou Xiaodong
Outcome results
None listed