severe traumatci brain injury
Conditions
Interventions
control group:traditional decompressive measure
study group:Controlled decompressive measure
Sponsors
Department of Neurosurgery, 101th Hospital of PLA, China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Adult patients with severe TBI, preoperative Glasgow coma score (GCS) of 3-8 underwent emergency craniectomy for haematoma removal; CT image showed supratentorial hematoma(s) and/or contusions with severe mass effect, press and distortion of the lateral ventricles and basal cistern, volume of haematoma at least 30ml. At least one pupil dilated; Legally authorized representative able to provide informed consent.
Exclusion criteria
Exclusion criteria: Brain swelling caused by anoxia or hypotension with minor intracranial bleeding after injury; Patients with coagulation disorders or a history of aspirin intake and some other organ malfunctions; Extensive multifocal cerebral hematoma; Uncommon injury location like hematoma of brain stem, ventricle,or diastema,etalissulcus of transverse sinus; Cases need for bilateral craniotomy at the beginning; Patients with preoperative GCS 3 and bilateral dilated pupils, showed no better or even worse in the treatment of emergency room, and presented with a attenuate respiration and blood pressure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| death rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence rate of intraoperative brain swelling;incidence rate of post traumatic cerebral infarction;incidence rate of delayed hematoma;GOS score in discharge;ADL score 6 month afer operation; | — |
Countries
China
Contacts
Public ContactYuhai Wang
Department of Neurosurgery, 101th Hospital of PLA, China
Outcome results
None listed