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Study of clinical efficacy and side effects of risperidone in the treatment of schizophrenics

Study of clinical efficacy and side effects of risperidone in the treatment of schizophrenics

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-TCC-09000584
Enrollment
Unknown
Registered
2009-11-10
Start date
2009-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Group A:Risperidone 2-8mg/d, taken once daily for 6 weeks
Group B:Alimentary control for 1-2 days before sampling (low protein, low fat, no eggs, no meat and no milk)

Sponsors

The Second Xiangya Hospital of Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosis in accordance with (CCMD-III) criteria,With PANSS>=60 or BPRS>=35, were schizophrenia and schizophreniform disorder; 2. Without a history of substance abuse (like alcohol), past or present neurological disease, or any other organic disturbance that might have interfered with the aim of the study; 3. First-episode or neuroleptic-free schizophrenics, with more than 1 month of washout; 4. ages vary from 18-50 years old.

Exclusion criteria

Exclusion criteria: Not accord with the including criteria or shed off during observation

Design outcomes

Primary

MeasureTime frame
Norepinephrine;gama-aminobutyric acid;5-Hydroxytryptamine;Dopamine;Glutamate;

Secondary

MeasureTime frame
5-Hydroxytindole-3-acetic acid;3,4-Dihydroxyphenylaceti acid;Homovanillic acid;Vanilmandelic acid;3,4-Dihydroxyphenylaceti acid;

Countries

China

Contacts

Public ContactHuan-De Li
lihuande1953@126.com+86 0731 84436720

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026