Normal pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant women with all the following conditions: 1. Aged between 18-45 years old; 2. Singleton pregnancy; 3. Pregnant women with gestational ages before 13+6 weeks, or between 20 and 24 weeks, or between 32 to 36 weeks, or 42 days after delivery.
Exclusion criteria
Exclusion criteria: 1. Women with structural heart disease and severe arrhythmia [usually including short or persistent ventricular tachycardia (VT), ventricular fibrillation (VF), atrial fibrillation (AF), II-III degree atrioventricular block AVB)]; 2. Multiple pregnancy; 3. Hypertensive disorders complicating pregnancy; 4. Gestational diabetes mellitus; 5. Definitely diagnosed of immune system diseases (such as systemic lupus erythematosus, etc.); 6. Hyperthyroidism or hypothyroidism (excluding subclinical hyperthyroidism and subclinical hypothyroidism); 7. Anemia (hemoglobin less than 90g/L); 8. Other serious respiratory, digestive, nervous, urinary, hematological, endocrine system diseases; 9. Participate in other interventional clinical trials within 3 months before the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| values scanned at left ventricular long axis: diameters of aortic root, left atrial, left ventricular end-diastole and left ventricular end-systole, thickness of interventricular septum and left ventricular posterior wall.;Pulmonary trunk;Right ventricular apical four-chamber view: right ventricular internal diameter, right atrial diameter, LVMI, TAPSE;Left ventricular systolic function: EF,FS,SV,CO;Left ventricular diastolic function: Mitral valve flow spectrum image: peak E and A, E/A, E peak deceleration time(EDT); Tissue Doppler image(TDI): Systolic peak velocity(S), Early diastolic peak velocity(e’), Late diastolic peak velocity(a’);Pulmonary artery systolic pressure; | — |
Countries
China
Contacts
Renji Hospital, Shanghai Jiao Tong University School of Medicine