atrial fibrillation
Conditions
Interventions
Sponsors
Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine;Department of Cardiovascular Surgery, East Hospital, Tongji University School o
Eligibility
Sex/Gender
Male
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: Normal group: Left atrial appendage:from 6 heart transplant donors Aged 45-75 years old male; Weight 55-75kg. Atrial fibrillation group: Left atrial appendage: from the endoscopic surgical excised left atrial appendage of 14 patients whose baseline are similar to the normal group;
Exclusion criteria
Exclusion criteria: Patients have other heart diseases, such as valvular diseases; combined with other organic heart disease such as coronary heart disease,dilated cardiomyopathy,congenital heart disease. Possible interventions in circRNA detection: tumor, chronic viral infection,immune disease, etc. Taking large doses drugs before the tests that may affect the outcome; Antibiotics, hormones,immunosuppressor, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CircRNA expression profile;biomarkers of artial fibrillation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mortality; | — |
Countries
China
Contacts
Public ContactYangyang Zhang
Shanghai East Hospital of Tongji University School; Tongji University School of Medicine
Outcome results
None listed