Fungal infection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged more than 18 years; 2. Using of voriconazole for treatment or prevention fungal infections in patients with liver dysfunction; 3. at least one voriconazole plasma Cmin.
Exclusion criteria
Exclusion criteria: 1. simultaneous use of another antifungal agent; 2. combination of rifampicin,isoniazid,phenytoin and other potent CYP450 inducers and inhibitors; 3. lack of compliance with the recommended dosage regimen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood concentration;Clinical index; | — |
Countries
China
Contacts
The Second Xiangya Hospital of Central South University?