Cardiovascular disease
Conditions
Interventions
group with brain injury and without brain injury:none
Sponsors
Xinqiao Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: First,patients with cardiac valve replacement and aortic dissection after cardiopulmonary bypass. Second, the age of patients ranges from 18 to 80 years old. Third, patients signed informed consent.;Inclusion criteria: First,patients with cardiac valve replacement and aortic dissection after cardiopulmonary bypass. Second, the age of patients ranges from 18 to 80 years old. Third, patients signed informed consent.;Inclusion criteria: First,patients with cardiac valve replacement and aortic dissection after cardiopulmonary bypass. Second, the age of patients ranges from 18 to 80 years old. Third, patients signed informed consent.;Inclusion criteria: First,patients with cardiac valve replacement and aortic dissection after cardiopulmonary bypass. Second, the age of patients ranges from 18 to 80 years old. Third, patients signed informed consent.;Inclusion criteria: First,patients with cardiac valve replacement and aortic dissection after cardiopulmonary bypass. Second, the age of patients ranges from 18 to 80 years old. Third, patients signed informed consent.
Exclusion criteria
Exclusion criteria: Preoperative brain trauma history, stoke, epilepsy, mental illness, brain tumor, multiple sclerosis, mental disorders and other brain diseases.;Exclusion criteria: Preoperative brain trauma history, stoke, epilepsy, mental illness, brain tumor, multiple sclerosis, mental disorders and other brain diseases.;Exclusion criteria: Preoperative brain trauma history, stoke, epilepsy, mental illness, brain tumor, multiple sclerosis, mental disorders and other brain diseases.;Exclusion criteria: Preoperative brain trauma history, stoke, epilepsy, mental illness, brain tumor, multiple sclerosis, mental disorders and other brain diseases.;Exclusion criteria: Preoperative brain trauma history, stoke, epilepsy, mental illness, brain tumor, multiple sclerosis, mental disorders and other brain diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| methylation state of MBP fragment; | — |
Secondary
| Measure | Time frame |
|---|---|
| myelin basic protein (MBP);neuron-specific enolase (NSE);Non-phosphorylated tau protein; | — |
Countries
China
Contacts
Public ContactXiao Yingbin;Xiao Yingbin;Xiao Yingbin;Xiao Yingbin;Xiao Yingbin ;;;;
Department of Cardiovascular Surgery, Xinqiao Hospital;Department of Cardiovascular Surgery, Xinqiao Hospital;Department of Cardiovascular Surgery, Xinqiao Hospital;Department of Cardiovascular Surgery, Xinqiao Hospital;Department of Cardiovascular Surgery, Xinqiao Hospital
Outcome results
None listed