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The role of urinary exosomes in the early diagnosis of renal tubular damage in diabetes mellitus

The role of urinary exosomes in the early diagnosis of renal tubular damage in diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RRC-17013033
Enrollment
Unknown
Registered
2017-10-19
Start date
2018-01-01
Completion date
Unknown
Last updated
2017-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic nephropathy

Interventions

case series:Nil

Sponsors

Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inpatients of type 2 diebetes are selected in the department of endocrinology and nephrology in the Second Hospital of Shandong University. These patients were divided into four groups by urinary albumin/creatinine ratio (UACR): normoalbuminuria group (DM, n=40,UACR 300mg/g creatinine) and renal insufficiency group(DN3,n=50, ACR?1.2mg/dl creatinine, with macroalbuminuria).

Exclusion criteria

Exclusion criteria: Exclusion criteria were as follows: tumours, urinary tract disorders, pregnancy, known renal diseases other than DKD, decompensated heart failure, chronic inflammatory diseases, prostatic diseases (in males), haematological diseases, liver diseases and recent myocardial infarction or unstable angina within past 6 months.

Design outcomes

Primary

MeasureTime frame
E-cadherin;Tamm-Horsfall protein;Tamm-Horsfall protein;MCP -1;—

Countries

China

Contacts

Public ContactSun Aili

Second Hospital of Shandong University

aillysn@163.com+86 13964039815

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026