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Research on changes of cerebral plasticity with carpal tunnel syndrome by EEG-fMRI multimodal exploration

The research of cerebral plasticity with carpal tunnel syndrome

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RRC-17012788
Enrollment
Unknown
Registered
2017-09-25
Start date
2014-11-04
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carpal tunnel syndrome

Interventions

Normal subjects group versus CTS group:Surgery: median nerve release

Sponsors

Shanghai Jin'an District Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patient group access criteria: (1) clinically diagnosed patients with carpal tunnel syndrome; (2) intelligence, language and visual and auditory function is normal; (3) age is not limited, men and women are not limited; 40-65 year old women priority included (4) right hand (5) Patient him/herself desired to improve the hand discomfort by surgery; (6) willing to accept including clinical physical examination, EEG, EMG and magnetic resonance examination, follow follow-up arrangements Control group selection criteria: (1) healthy people; (2) intelligence, language and visual and auditory function is normal; (3) Any age men and women; age and sex matched with experimental group; (4) right hand; (5) willing to accept including clinical physical examination, EEG, EMG and magnetic resonance examination, follow follow-up arrangements.

Exclusion criteria

Exclusion criteria: Patient group exclusion criteria: (1) have the following diseases: diabetes, cervical spondylosis, rheumatism and rheumatoid arthritis, peripheral neuritis, wrist trauma, chronic pain, depression and other mental illness or disorder, cerebrovascular disease, brain trauma, Kindergarten, Alzheimer's disease, multiple sclerosis, severe systemic disease; (2) the presence of metal implants, pacemakers, tattoos; (3) to participate in this study before any form of treatment (including other diseases), such as physical therapy, taking drugs; (4) no intention of surgical treatment; (5) can not follow the follow-up arrangements; Control group exclusion criteria: (1) have the following diseases: diabetes, cervical spondylosis, rheumatism and rheumatoid arthritis, peripheral neuritis, wrist trauma, chronic pain, depression and other mental illness or disorder, cerebrovascular disease, brain trauma, Kindergarten, Alzheimer's disease, multiple sclerosis, severe systemic disease. (2) the presence of metal implants, pacemakers, tattoos; (3) to participate in this study before any form of treatment or medication history; (4) can not follow the follow-up arrangements.

Design outcomes

Primary

MeasureTime frame
fMRI:Activation;

Secondary

MeasureTime frame
fMRI:Diffusion Tensor Imaging;fMRI:Functional Connectivity;fMRI:Resting-State;EEG;

Countries

China

Contacts

Public ContactWendong Xu

Department of Hand Surgery, Huashan Hospital, Fudan University

xuwendong_huashan@163.com+86 021-61578012

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026