Laryngopharyngeal reflux disease
Conditions
Interventions
gastroesophageal reflux disease :multichannel intraluminal impedance and Dx-pH text
Laryngopharyngeal reflux disease:multichannel intraluminal impedance and Dx-pH text
normal population :multichannel intraluminal impedance and Dx-pH text
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) The subject must voluntarily participate in the study and observe the study requirements and voluntarily sign a written informed consent form; (2) Subject aged 18 to 70 years old; (3) male and female Chinese people; (4) the new diagnosed GERD patients (the diagnostic criteria refer to the guideline developed by World Gastroenterology Organization in 2015); (5) with typical LPS, more than 3 months duration, high incidence of recurrence, the stubborn symptoms.
Exclusion criteria
Exclusion criteria: (1) patients with central nervous system diseases,severe cardiovascular diseasecoagulopathy disorders or other diseases; (2) with surgical history of esophageal or stomachor diagnosed with esophageal stenosis or short esophagus; (3) unable to tolerate esophageal pressure monitoring or other relevant examination and treatment; (4) patients with achalasia or gastrointestinal malignancy; (5) with a history of mental illness, Confrontational character,or other emotional or intellectual problems may jeopardize the validity of informed consent participation in the study; (6) Pregnant or lactating women; (7) patients refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| multichannel intraluminal impedane;Dx-pH;reflux finding score;reflux finding score; | — |
Secondary
| Measure | Time frame |
|---|---|
| pepsinum;Airway dynamic monitoring; | — |
Countries
China
Contacts
Public ContactZhang Xiaowen
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed