Type 2 diabetes mellitus
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: A total of 4802 subjects participated in the initial (first phase) study that was performed between 2011 and 2012. Follow-up of these participants takes place at 4-year intervals. A total of 4274 individuals participated in both the first phase (2011–2012, used as baseline in the present analysis) and second phase (2015–2016, used as follow-up in the present analysis) of the study. Of the 3273 participants with normal glucose tolerance at baseline, we selected all those who developed type 2 diabetes (n=154) during a 4-year follow up. For each of these individuals, we selected a control group (with normal glucose tolerance) with a propensity score matching at a 1:1 ratio. Control subjects were matched for age, gender, fasting plasma glucose levels and 2h plasma glucose.
Exclusion criteria
Exclusion criteria: Subjects lacking laboratory or anthropometric data and those with known or newly diagnosed diabetes or prediabetes in the baseline study were excluded.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| HOMA-IR;The incidence rates of type 2 diabetes; | — |
Primary
| Measure | Time frame |
|---|---|
| Serum betatrophin levels; | — |
Countries
China
Contacts
the First People's Hospital of Xuzhou, Jiangsu