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Serum betatrophin concentrations and risk of developing diabetes: a nested case–control study

Serum betatrophin concentrations and risk of developing diabetes: a nested case–control study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RRC-17011586
Enrollment
Unknown
Registered
2017-06-07
Start date
2017-07-01
Completion date
Unknown
Last updated
2017-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

Type 2 diabetes group:Administering the questionnaire
Control group:Administering the questionnaire

Sponsors

the First People's Hospital of Xuzhou, Jiangsu
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: A total of 4802 subjects participated in the initial (first phase) study that was performed between 2011 and 2012. Follow-up of these participants takes place at 4-year intervals. A total of 4274 individuals participated in both the first phase (2011–2012, used as baseline in the present analysis) and second phase (2015–2016, used as follow-up in the present analysis) of the study. Of the 3273 participants with normal glucose tolerance at baseline, we selected all those who developed type 2 diabetes (n=154) during a 4-year follow up. For each of these individuals, we selected a control group (with normal glucose tolerance) with a propensity score matching at a 1:1 ratio. Control subjects were matched for age, gender, fasting plasma glucose levels and 2h plasma glucose.

Exclusion criteria

Exclusion criteria: Subjects lacking laboratory or anthropometric data and those with known or newly diagnosed diabetes or prediabetes in the baseline study were excluded.

Design outcomes

Secondary

MeasureTime frame
HOMA-IR;The incidence rates of type 2 diabetes;

Primary

MeasureTime frame
Serum betatrophin levels;

Countries

China

Contacts

Public ContactWang Zhaoling

the First People's Hospital of Xuzhou, Jiangsu

dyywzl@126.com+86 13852103069

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026