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Noninvasive chromosome screening(NICS) of human embryos by genome sequencing of embryo culture medium for in vitro fertilization:a multicenter-clinical trial,the fourth study was a case-control study

Noninvasive chromosome screening(NICS) of human embryos by genome sequencing of embryo culture medium for in vitro fertilization:a multicenter-clinical trial

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RRC-17010396
Enrollment
Unknown
Registered
2017-01-11
Start date
2017-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

screening of human embryos by genome sequencing

Interventions

Pregnancy group:Retrospective study of non intervention
None pregnancy group:Retrospective study of non intervention

Sponsors

Nanjing General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. aged between 35 and 45 years; 2. aged between 35 and 45 years and embyos only by ICSI(1-2 must satisfy one of these); 3. Agreed with selective single blastocyst frozen-thawed embyo transfer; 4. the number of eligible blastocysts by morphology (BC,CB or better)were 2 or more for transplant; 5. be willing to participate in this study and to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. patients with contraindications for assisted reproductive technology; 2. uterine cavity abnormalities; 3. endometrial injury; 4. endometrial hyperplasia; 5. intrauterine fluid; 6. adenomyosis of the uterus; 7. hydrosalpinx; 8. repeated implantation failure; 9. recurrent miscarriage; 10. chromosomal abnormalities; 11. any other conditions that investigators considered not suitable to participate in this study.

Design outcomes

Primary

MeasureTime frame
Evaluate and analyze the factors that affect the live birth rate;

Countries

China

Contacts

Public ContactBING YAO

Nanjing General Hospital

yaobing@nju.edu.cn+86 13815853296

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026