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ERCC1 and XRCC1 but not XPA single nucleotide polymorphisms correlate with response to chemotherapy in endometrial carcinoma: a case records based case-control study

ERCC1 and XRCC1 but not XPA single nucleotide polymorphisms correlate with response to chemotherapy in endometrial carcinoma: a case records based case-control study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RRC-16009412
Enrollment
Unknown
Registered
2016-10-14
Start date
2016-10-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometrial carcinoma

Interventions

The case group:Detections of single nucleotide polymorphism
The control group:Detections of single nucleotide polymorphism

Sponsors

The 2nd Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: All patients underwent extrafascial hysterectomy with bilateral adnexectony and pelvic cavity abdominal aorta lymph node dissection. Also, all patients with complete clinical data neither accept any treatment before hospital admission nor suffer from other malignant tumors. And they had no mental disorder and unconscious disorders, blood coagulation dysfunction, severe cardiac, cerebral vessels disease and liver and kidney dysfunction. Meanwhile, the patients did not accept other antineoplastic treatments before treatment by cisplatin plus fluorourcil.

Exclusion criteria

Exclusion criteria: (1) patients without complete clinical data; (2) patients with preoperative radiotherapy, chemotherapy; (3) patients accompanied with other malignant tumors.

Design outcomes

Primary

MeasureTime frame
SNP genotype;

Countries

China

Contacts

Public ContactChen Liang

The 2nd Affiliated Hospital of Harbin Medical University

acdfj18678@163.com+86 15645630333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026