Healthy male
Conditions
Interventions
Group B:Give placebo for 6 d, tid, 3 tablets once
give talinolol 1 tablet in the seventh day
Group A:Give compound glycyrrhizin for 6 d, tid, 3 tablets once
Sponsors
The Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Male
Age
20 Years to 24 Years
Inclusion criteria
Inclusion criteria: 1. Each subject was ascertained to be in good health as assessed by a medical history, physical examination, routine laboratory testing (which included hematologic, serum chemical, and urine testing), and a standard 12-lead electrocardiogram; 2. Only subjects with normal PR interval, resting pulse rate more than 55 beats/min, and a systolic/ diastolic blood pressure of more than 105/60mm Hg were recruited.
Exclusion criteria
Exclusion criteria: 1. Subject had significant illnesses within the preceding 28 days; 2. Routinely used medications; 3. History of cardiac, renal, hepatic, or gastrointestinal disease or of drug or alcohol abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum concentration of talinolol; | — |
Countries
China
Contacts
Public ContactHuan-De Li
Outcome results
None listed