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The content of SLC26A3 and NHERF4 were found in mucosa of acute Inflammatory bowel disease and irritable bowel syndrome

The role and mechanism of PI3K/akt-nherf4-slc26a3 in the barrier of intestinal mucous barrier of recurrent ulcerative colitis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RPC-17013191
Enrollment
Unknown
Registered
2017-10-31
Start date
2017-11-01
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory bowel disease, irritable bowel syndrome

Interventions

Sponsors

Xinjiang Shihezi University First Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Based on the the 'consensus on diagnosis and treatment of inflammatory bowel disease (guangzhou,2012)'as the diagnostic criteria of the standard of diagnosis. The inclusion criteria are in accordance with the diagnostic criteria of UC and the data is relatively complete, with age, gender and ethnicity as the matching conditions, and the heart, lung, skin and immune diseases are excluded.;Inclusion criteria: Based on the the 'consensus on diagnosis and treatment of inflammatory bowel disease (guangzhou,2012)'as the diagnostic criteria of the standard of diagnosis. The inclusion criteria are in accordance with the diagnostic criteria of UC and the data is relatively complete, with age, gender and ethnicity as the matching conditions, and the heart, lung, skin and immune diseases are excluded.;Inclusion criteria: Based on the the 'consensus on diagnosis and treatment of inflammatory bowel disease (guangzhou,2012)'as the diagnostic criteria of the standard of diagnosis. The inclusion criteria are in accordance with the diagnostic criteria of UC and the data is relatively complete, with age, gender and ethnicity as the matching conditions, and the heart, lung, skin and immune diseases are excluded.;Inclusion criteria: Based on the the 'consensus on diagnosis and treatment of inflammatory bowel disease (guangzhou,2012)'as the diagnostic criteria of the standard of diagnosis. The inclusion criteria are in accordance with the diagnostic criteria of UC and the data is relatively complete, with age, gender and ethnicity as the matching conditions, and the heart, lung, skin and immune diseases are excluded.;Inclusion criteria: Based on the the 'consensus on diagnosis and treatment of inflammatory bowel disease (guangzhou,2012)'as the diagnostic criteria of the standard of diagnosis. The inclusion criteria are in accordance with the diagnostic criteria of UC and the data is relatively complete, with age, gender and ethnicity as the matching conditions, and the heart, lung, skin and immune diseases are excluded.

Exclusion criteria

Exclusion criteria: UC patients with intestinal tuberculosis and other infectious diseases, such as ischemic bowel disease, drugs and other causes of non-primary enteritis; Allergic constitution; The disease is more severe and causes malnutrition; Colorectal cancer; Combined with heart, liver, spleen, lung, kidney and other severe primary disease.;Exclusion criteria: UC patients with intestinal tuberculosis and other infectious diseases, such as ischemic bowel disease, drugs and other causes of non-primary enteritis; Allergic constitution; The disease is more severe and causes malnutrition; Colorectal cancer; Combined with heart, liver, spleen, lung, kidney and other severe primary disease.;Exclusion criteria: UC patients with intestinal tuberculosis and other infectious diseases, such as ischemic bowel disease, drugs and other causes of non-primary enteritis; Allergic constitution; The disease is more severe and causes malnutrition; Colorectal cancer; Combined with heart, liver, spleen, lung, kidney and other severe primary disease.;Exclusion criteria: UC patients with intestinal tuberculosis and other infectious diseases, such as ischemic bowel disease, drugs and other causes of non-primary enteritis; Allergic constitution; The disease is more severe and causes malnutrition; Colorectal cancer; Combined with heart, liver, spleen, lung, kidney and other severe primary disease.;Exclusion criteria: UC patients with intestinal tuberculosis and other infectious diseases, such as ischemic bowel disease, drugs and other causes of non-primary enteritis; Allergic constitution; The disease is more severe and causes malnutrition; Colorectal cancer; Combined with heart, liver, spleen, lung, kidney and other severe primary disease.

Design outcomes

Primary

MeasureTime frame
SLC26A3;NHERF4;

Countries

China

Contacts

Public ContactXu Lihong;Xu Lihong;Xu Lihong;Xu Lihong;Xu Lihong ;;;;

Xinjiang Shihezi University Medical School;Xinjiang Shihezi University Medical School;Xinjiang Shihezi University Medical School;Xinjiang Shihezi University Medical School;Xinjiang Shihezi University Medical School

xueli_2006@126.com;xueli_2006@126.com;xueli_2006@126.com;xueli_2006@126.com;xueli_2006@126.com+86 13579748283;+86 13579748283;+86 13579748283;+86 13579748283;+86 13579748283

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026