Functional magnetic resonance study of brain network mechanism in persistent somatoform pain disorder

Status

Recruiting

Phases

Phase 4

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-RPC-17012990

Enrollment

Unknown

Registered

2017-10-15

Start date

2017-10-20

Completion date

Unknown

Last updated

2017-10-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

persistent somatoform pain disorder

Interventions

patients: duloxetine sustained-release capsules

normal control:none

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) meet diagnostic criteria of persistent somatoform pain disorder in ICD-10 (International Statistical Classification of Diseases and Related Health Problems, 10th Revision, 1992); (2) Pain duration more than 6 months, at least 4 days of pain in 1 week, each pain duration more than 2 hours; (3) Visual Analogue Scale (VAS) score more than 3points; (4) the age of 18-60 years; (5) Have a certain reading and understanding ability to complete the study; (6) At least 1 month without taking any psychotropic drugs; (7) right-hand dominance; (8) patients agree to sign clinical use informed consent.

Exclusion criteria

Exclusion criteria: (1) presence of pain symptoms due to severe somatic diseases; (2) combined cardiovascular, brain, liver, kidney, hematopoietic system or other serious diseases, severe infections, malignant tumors, or other diseases that may have an impact on the test; (3) alcohol or other drug abusers; (4) presence of mental diseases (such as affective disorder, suicidal depression, anxiety disorder, phobic anxiety disorder, obsessive compulsive disorder, and posttraumatic stress disorder); (5) preparing pregnant, pregnant or lactating women; (6) participation in other clinical trials within past 4 weeks; (7) indications as evidenced by magnetic resonance imaging (MRI) of cerebral atrophy diagnosed by a radiologist who visually analyzed the MRI images on the scene.

Design outcomes

Primary

Measure	Time frame
Visual Analogue Pain Rating Scale, VAS;the Medical Outcomes Study Pain Measurement, MOSPM;McGill Pain Questionnaires, MPQ;Hamilton Anxiety Scale, HAMA;Hamilton depression scale, HAMD;the Short Form-36 Health Survey, SF-36;Repeatable Battery for the Assessment of Neuropsychological Status, RBANS;Functional magnetic resonance ;	—

Countries

China

Contacts

Public ContactYang Hailong

Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing

psydoctoryhl@163.com+86 18651698898

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026