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The identification of genes and mutations for genetic susceptibilty to Noise induced deafness and investigation of the molecular mechanisms

The identification of genes and mutations for genetic susceptibilty of noise-induced hearing loss and investigation of the molecular mechanisms

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RPC-17012580
Enrollment
Unknown
Registered
2017-09-05
Start date
2017-09-30
Completion date
Unknown
Last updated
2018-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

noise-induced hearing loss

Interventions

sensitive group:N/A
resistant group:N/A

Sponsors

Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Individual between 18 ~ 60 years old; 2. Individual who has exposed to occupational noise from 1 to 20 years; 3. Individuals whose occupational noise exposure intensity is 80 dB (A) or higher.

Exclusion criteria

Exclusion criteria: 1. Individual who has a history of head or ear injury, familial or congenital deafness, ototoxic drug use, middle ear disease, tympanic membrane perforation, etc.; 2. Individual whose binaural auditory threshold is greater than 40dB.

Design outcomes

Primary

MeasureTime frame
Pure tone audiometry;genotype sequence;—

Secondary

MeasureTime frame
acoustic immitance;acoustic immitance;—

Countries

China

Contacts

Public ContactYin Shankai

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

yinshankai@china.com+86 18930177096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026