Primary infertility
Conditions
Interventions
follicle phase group:Remifentanil target concentration
luteal phase group:Remifentanil target concentration
Sponsors
Women's Hospital, Zhejiang University
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Adult fertile women, aged 18-40 yr, ASA physical status I-II, with regular menstrual cycles (a regular cycle was defined as lasting 23-35 days with no variations more than 2 days)(21), receiving general anesthesia for elective gynaecological laparoscopy surgery were enrolled.
Exclusion criteria
Exclusion criteria: BMI33; pregnant; less than two months from termination of pregnancy;receiving hormones or medications affecting ovulation in 6 weeks before surgery;(16) chronic or acute (within 48 h) intake of psychotropic drugs; use of CNS-active medication or alcoholism or opioids;presence of any disease of cardiac ,pulmonary,hepatic, renal, or neurological. In addition ,patients were also excluded if local anesthetics, atropine, epinephrine, or other vaso-active medications were used during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| female sex hormone;EC50 of remifentanil;SPI;Entropy index;Blood pressure;Heart rate; | — |
Countries
China
Contacts
Public ContactYanhong Zhou
Women's Hospital, Zhejiang University
Outcome results
None listed