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The influence of tea intake, mTOR signaling pathway genetic polymorphism and their interaction on mild cognitive impairment in patient with cerebral small vessel disease

The influence of tea intake, mTOR signaling pathway genetic polymorphism and their interaction on mild cognitive impairment in patient with cerebral small vessel disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-RPC-16008270
Enrollment
Unknown
Registered
2016-04-12
Start date
2016-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral small vessel disease

Interventions

case vs control :Non

Sponsors

The Second Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Presence and location of lacunes were recorded by a consultant neuroradiologist, based on T1W, T2W, FLAIR images and diffusion weighted imaging (DWI). A chronic lacune was defined as a cerebrospinal fluid-filled cavity, not hyper-intense on DWI, 3 to 15 mm in diameter, with a surrounding rim of high signal intensity on FLAIR following a vascular distribution

Exclusion criteria

Exclusion criteria: Exclusion criteria were an acute infarction with hyper-intense on DWI; cortical and/or subcortical nonlacunar infarcts or intracerebral hemorrhage identified by MRI; severe cardiovascular, renal, hepatic, neoplastic or chronic disease; major psychiatric comorbidity; major depression, and dementia.

Design outcomes

Primary

MeasureTime frame
Cognitive function;—

Countries

China

Contacts

Public ContactYanfeng Wu

The Second Affiliated Hospital of Nanjing Medical University

yanfengwunj@163.com+86 18118995531

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026