asthma
Conditions
Interventions
neutrophilic:sputum induce
non-neutrophilic:sputum induce
Sponsors
The second affiliated hospital of third military medical university
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Informed consent; 2. Diagnosed with asthma according to the criteria of GINA(2014); 3. Aged 18-75.
Exclusion criteria
Exclusion criteria: 1. Use of systemic corticosteroids for regular treatments or within 4 weeks; 2. Exacerbations within 4 weeks; 3. Respiratory infections within 4 weeks; 4. Use of antibiotics within 4 weeks; 5. Smoking or quit smoking less than 1 year and had a less than 5 pack-year smoking history; 6. Combined bronchiectasis (seen in chest X ray),TB or other serious diseases such as cancer; 7. Other conditions unavailable to participate in research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FVC;FEV1;FEV1/FVC;ACT score;total number of sputum;sputum neutrophils;sputum eosinophils;Sputum Lymphocyte;Sputum Macrophage;copy number of bacteria;diversity; | — |
Secondary
| Measure | Time frame |
|---|---|
| symptom; | — |
Countries
China
Contacts
Public ContactChangzheng Wang
Outcome results
None listed