multiple system atrophy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) MSA group: collected in Nanjing Medical University affiliated brain hospital neurology hospital or outpatient treatment MSA-P And MSA-C patients were enrolled in 40 cases of subtypes. Inclusion criteria: ? meet Gilman diagnostic criteria; ? course of = 5 years, the age of onset = 75 years; ? exclude other neurological diseases, no ataxia or Parkinson's disease Family history; ? no memory loss, intelligent obstacles; ? right hand. (2) healthy control group: randomly selected in the community 40 cases of age, gender, education, matching healthy elderly, no Memory loss, mental retardation, no serious heart, brain, kidney disease history, no history of alcohol and drug abuse, T2 plus There is no cerebral infarction or other vascular damage, are right hand.
Exclusion criteria
Exclusion criteria: Brain injury, encephalitis, drugs, metabolism and other neurological degeneration diseases secondary to Parkinson's syndrome, no other mental disorders and mental retardation, no serious heart, brain, kidney disease history, no alcohol and drug abuse history, T2 There was no cerebral infarction or other vascular injury on the weighted image
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| scale;T1 structure, diffusion tensor imaging (DTI), resting functional magnetic resonance (MRI); | — |
Contacts
Nanjing Brain Hospital