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Functional magnetic resonance study of neurodegenerative diseases

Effects of different frequency repetitive transcranial magnetic stimulation on brain function connectivity in patients with multiple system atrophy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROR-17012744
Enrollment
Unknown
Registered
2017-09-19
Start date
2017-10-01
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

multiple system atrophy

Interventions

HC:Sham TMS

Sponsors

Nanjing Brain Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: (1) MSA group: collected in Nanjing Medical University affiliated brain hospital neurology hospital or outpatient treatment MSA-P And MSA-C patients were enrolled in 40 cases of subtypes. Inclusion criteria: ? meet Gilman diagnostic criteria; ? course of = 5 years, the age of onset = 75 years; ? exclude other neurological diseases, no ataxia or Parkinson's disease Family history; ? no memory loss, intelligent obstacles; ? right hand. (2) healthy control group: randomly selected in the community 40 cases of age, gender, education, matching healthy elderly, no Memory loss, mental retardation, no serious heart, brain, kidney disease history, no history of alcohol and drug abuse, T2 plus There is no cerebral infarction or other vascular damage, are right hand.

Exclusion criteria

Exclusion criteria: Brain injury, encephalitis, drugs, metabolism and other neurological degeneration diseases secondary to Parkinson's syndrome, no other mental disorders and mental retardation, no serious heart, brain, kidney disease history, no alcohol and drug abuse history, T2 There was no cerebral infarction or other vascular injury on the weighted image

Design outcomes

Primary

MeasureTime frame
scale;T1 structure, diffusion tensor imaging (DTI), resting functional magnetic resonance (MRI);

Contacts

Public ContactJingping Shi

Nanjing Brain Hospital

profshijp@163.com+86 025 82296370

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026