hepatic carcinoma
Conditions
Interventions
1: block the vena cava before touching liver in the tumor side
2:Not block the vena cava before touching liver in the tumor side
Sponsors
Tianjin First Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: The subject will be included,who must meet all the following criteria: 1. Patients must confirmed hepatic carcinoma which TNM stage was II/III; 2. Aged 18 to 75 years; 3. Patient must provide the blood sample, and the amount should be able to meet the requirements of DNA extraction and quality control; 4. The heart, lung, kidney and other major organs of the patients meet the requirements of this study; 5. Patients must have the ability to understand and the willingness to sign a written informed consent document, willing to cooperate with the follow-up.
Exclusion criteria
Exclusion criteria: Either of the following which is not one of exclusion criteria will not be enrolled: 1. Other malignancies in the past five years;except cured basal cell carcinoma, cervical carcinoma in situ, localized prostate cancer with surgical treatment or breast ductal carcinoma in situ with surgical resection; 2. Patients with extrahepatic distal metastases; 3. Patients with infection; 4. Cognitive ability and psychological abnormality; 5. Other serious diseases that researchers believe the subject can not be enrolled; 6. Use other test drugs or participate in other clinical trials; 7. Preoperative acceptance anti-tumor therapy, such as intubation chemotherapy, anhydrous alcohol injection, radiofrequency ablation team and others.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time between ctDNA detection and clinical relapse;cfDNA concentration;tumor mutation load;the level of AFP;OS;Recurrence rate;relapse free survival;genetic mutation; | — |
Countries
China
Contacts
Public ContactJiangwen Tao
Tianjin First Central Hospital
Outcome results
None listed