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The study of CircRNA as non-valvular persistent atrial fibrillation markers in blood

Analysis of the expression profile of CircRNA and the study of biomarkers of artial fibrillation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17014218
Enrollment
Unknown
Registered
2017-12-30
Start date
2017-12-29
Completion date
Unknown
Last updated
2018-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

Sponsors

Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine;Department of Cardiovascular Surgery, East Hospital, Tongji University School o
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: Normal group: 1. Blood samples: peripheral blood of normal healthy people without underlying diseases. 2. Aged 45-75 years old male; Weight 55-75kg. Atrial fibrillation group: Blood samples: peripheral blood of patients with AF whose baseline are similar to the normal group.

Exclusion criteria

Exclusion criteria: Patients have other heart diseases, such as valvular diseases; combined with other organic heart disease such as coronary heart disease,dilated cardiomyopathy,congenital heart disease. Possible interventions in circRNA detection: tumor, chronic viral infection,immune disease, etc. Taking large doses drugs before the tests that may affect the outcome; Antibiotics, hormones, immunosuppressors, etc.

Design outcomes

Primary

MeasureTime frame
RNA(circRNA) expression;Mortality;Survival time;

Countries

China

Contacts

Public ContactYangyang Zhang

Shanghai East Hospital of Tongji University School; Tongji University School of Medicine

zhangyangyang_wy@vip.sina.com+86 13818132320

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026