Schizophrenia
Conditions
Interventions
Schizophrenia Group:None
Prodromal Group:None
Healthy Controls:None
Sponsors
Brain Hospital affiliated with Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged between 18 and 45 years old; (2) Three groups will be recruited, patients fulfilled the diagnostic criteria for schizophrenia (DSM-5), individuals identified with clinical high risk(CHR) by the SIPS/SOPS (Structured Interview for Prodromal Symptoms and the Scale of Prodromal Syndromes), healthy controls with a negative family history of mental disorders matched to the other two groups by age, gender, and education; (3) The primary school education degree and above; (4) Subjects (or their guardians) must be signed informed consent, showing that they already understand the research and the purpose of the program and voluntarily participated in this study.
Exclusion criteria
Exclusion criteria: (1) Combined with serious physical disease; (2) Current or past alcohol or substance dependence; (3) With mental retardation; (4) One who is excited, impulsivity, aggression; (5) One who had suicidal behavior or existing suicide attempts; (6) One who underwent modified electroconvulsive therapy or psychological treatment system within 6 months prior to screening; (7) One who had visual, auditory damage and is still unable to complete the test after correction; (8) Other situations not to participate in training or evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MicroRNA expression;Structural and functional magnetic resonance imaging;Rest-state and event-related magnetic fields;SAPS, SANS;HAMD;PANSS;MCCB; | — |
Countries
China
Contacts
Public ContactShiping Xie
Brain Hospital affiliated with Nanjing Medical University
Outcome results
None listed