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The effects of transcutaneous electrical acupoint stimulation on individual differences in analgesic effects: Analysis the effect of µ opioid receptor gene polymorphism

The effects of transcutaneous electrical acupoint stimulation on individual differences in analgesic effects: Analysis the effect of µ opioid receptor gene polymorphism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17013882
Enrollment
Unknown
Registered
2017-12-13
Start date
2018-01-01
Completion date
Unknown
Last updated
2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic myomectomy

Interventions

two:TEAS

Sponsors

The First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: There was no history of smoking alcohol abuse, no history of vascular disease, kidney disease, liver disease and diabetes mellitus, no history of chronic pain, no history of using of analgesic medication and liver enzyme inducer medication. Preoperative blood routine, urine routine, blood biochemistry, chest X-ray, ECG, rheumatology and hyperthyroidism full examination were normal; without preoperative chronic disease of endocrine metabolism,circulation,respiratory, urinary system; normal liver and kidney function; without acute inflammation in the last two weeks. All the operations were performed by the same group of doctors.

Exclusion criteria

Exclusion criteria: Body mass index is larger than 30kg/m2, BHR<50 /min, ASA more than III grade level; reoperation; liver and kidney dysfunction, in late pregnancy; acute inflammation, Intra-abdominal infection, peritonitis; auditory abnormalities, mental hypoplasia, psychiatric patients; long-term use of opioids or benzodiazepines; in this study,Allergic to any drug in the study;operation time is less than 30min or more than 120min.Cutaneous lesions in the puncture site; nerve tissue or disease affecting the region of dermal puncture;acupuncture treatment within the last 4 months;a history of heart disease or transplanted devices such as pacemakers;participation in other clinical trials within the last 3 months; Refusal to participate in the trial or provide informed consent.

Design outcomes

Primary

MeasureTime frame
pain;

Countries

China

Contacts

Public ContactJia Yanan

The First Affiliated Hospital of Wenzhou Medical University

1807904704@qq.com+86 18267852961

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026