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Study on early screening and warning of postoperative cognitive dysfunction in cerebrospinal fluid and blood

Study on early screening and warning of postoperative cognitive dysfunction in cerebrospinal fluid and blood

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17013783
Enrollment
Unknown
Registered
2017-12-08
Start date
2018-01-01
Completion date
Unknown
Last updated
2017-12-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Cognitive Dysfunction

Interventions

Case series:Nil

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1) Aged 60 and 85 years; 2) ASA I ~ II; 3) The simple mental state scale (MMSE) scored =17 points; 4) The patients and their families or guardians have informed consent of the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1) Compound injury: multiple fracture, trauma of other parts and injury of the outside of the brain; 2) Anaesthetic contraindications in the spinal canal: the coagulant dysfunction, thrombocytopenia, the vertebral canal is occupied, puncture site infection, etc; 3) With severe physical organic disease (such as severe liver and kidney disease, diabetes, kidney stones, close Angle glaucoma), as well as the obvious history of drug allergy or other mental illnesses including alcohol dependence; 4) Do not agree to participate in this study.

Design outcomes

Primary

MeasureTime frame
short cognitive performance test, Syndrom-Kurztest, SKT;Boston naming test, BNT;trail making test, TMT;Benton visual retention test, BVRT;Purdue pegboard test, PPT;

Countries

China

Contacts

Public ContactChen Chunru

Ningbo First Hospital

ccr02@163.com+86 13819842325

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026