Postoperative Cognitive Dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Aged 60 and 85 years; 2) ASA I ~ II; 3) The simple mental state scale (MMSE) scored =17 points; 4) The patients and their families or guardians have informed consent of the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1) Compound injury: multiple fracture, trauma of other parts and injury of the outside of the brain; 2) Anaesthetic contraindications in the spinal canal: the coagulant dysfunction, thrombocytopenia, the vertebral canal is occupied, puncture site infection, etc; 3) With severe physical organic disease (such as severe liver and kidney disease, diabetes, kidney stones, close Angle glaucoma), as well as the obvious history of drug allergy or other mental illnesses including alcohol dependence; 4) Do not agree to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| short cognitive performance test, Syndrom-Kurztest, SKT;Boston naming test, BNT;trail making test, TMT;Benton visual retention test, BVRT;Purdue pegboard test, PPT; | — |
Countries
China
Contacts
Ningbo First Hospital