non-alcoholic fatty liver disease
Conditions
Interventions
Case series:None
Sponsors
the First Affiliated Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75, no limitation in sex and national; 2. BMI < 40kg/m2; 3. Liver pathology shows FLD; 4. Abnormal ALT, but <5ULNs; 5. No alcohol drinking history or daily alcohol intake <20 g for males and 10 g for females; 6. Patients understand and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Co-exsit other acute or chronic liver diseases, such as viral hepatitis, hereditary hemochromatosis, Wilson's disease, alcoholic liver disease, drug-induced liver disease, autoimmune liver disease, et al.; 2. Heart failure with grade II/III/IV; 3. Other organs failure, such as lung, liver, kidney, brain; 4. Dyscrasia; 5. Disuse-induced muscle atrophy 6. Disorder of gastrointestinal function such as absorption of disorder, malnutrition; 7. With heart pacemaker; 8. Non-controlled hypothyroidism; 9. HIV-Ag/Ab positive; 10. Alcoholic abuse or drug abuse; 11. Other malignancies, except early thyroid carcinoma; 12. Other conditions not suitable for this clinical research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver biopsy;Body Composition;FibroScan;Liver function;blood lipids;glycosylated hemoglobin;blood glucose;fasting insulin;BMI;Waist circumference;hip circumference;wrist circumference;Abdominal MRI; | — |
Countries
China
Contacts
Public ContactZheng Ming-Hua
the First Affiliated Hospital of Wenzhou Medical University
Outcome results
None listed