Skip to content

Effect of drug intervention on postpartum depression

Effect of dexmedetomidine on maternal intervention in cesarean section for postpartum depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-ROC-17013357
Enrollment
Unknown
Registered
2017-11-13
Start date
2017-11-20
Completion date
Unknown
Last updated
2019-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postpartum depression

Interventions

dexmedetomidine group:After delivery, participants received 0.5ug/kg intravenous dexmedetomidine (Infusion speed was 0.375ml/kg.h and infusion time was 20min).The PCIA protocol was 150ug sufentanil +
control group:After delivery, participants received 0.5ug/kg intravenous physiological saline immediately(Infusion speed was 0.375ml/kg.h and infusion time was 20min).,The PCIA protocol consisted of 1

Sponsors

the Anesthesia Department of the Third Xiangya Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Pregnant women over 18 years old ; 2. ASA II grade; 3. Be able to communicate with people normally 4. Voluntary and signed informed consent

Exclusion criteria

Exclusion criteria: 1. history of bipolar orpsychotic disorder; 2. homicidal state; 3. allergic to a2 -adrenergic receptor agonists; 4. an estimated intra-operative blood loss more than 800ml; 5. preoperative heart rate less than 50bpm with cardiac conduction or rhythm abnormalities; 6. drugs and/or alcohol abuse within the past 6 months.

Design outcomes

Primary

MeasureTime frame
EPDS;self-harm idea;

Secondary

MeasureTime frame
Ramsay sedation scores;Digital pain score;insomnia severity index;

Countries

China

Contacts

Public ContactDuan KM, Wang SY

the Anesthesia Department of the Third Xiangya Hospital

duankaiming@126.com+86 13974850936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026