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A randomized, single-blind, single-center, prospective cohort study of the application of gastric antrum combined with gastric cancer in the eradication of Helicobacter pylori eradication

A randomized, single-blind, single-center, prospective cohort study of the application of gastric antrum combined with gastric cancer in the eradication of Helicobacter pylori eradication

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17013219
Enrollment
Unknown
Registered
2017-11-02
Start date
2019-11-01
Completion date
Unknown
Last updated
2017-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Helicobacter pylori infection

Interventions

Single site sampling group versus Double position sampling group:no

Sponsors

Huzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 70 years old, men and women are not limited; 2. Due to abdominal pain, bloating, acid reflux, belching, nausea, vomiting, heartburn, chest pain, black and so on discomfort symptoms of HP-related diseases; 3. Antibiotics, bismuth, H2 receptor antagonists, or PPI are not used in the last two weeks; 4. Urine breath test was positive; 5. Agreed to endoscopy to take gastric mucosal biopsy specimens were HP culture and drug sensitivity test; 6. Agreed to follow the initial treatment of HP eradication therapy and are willing to follow the doctor's follow-up survey of eradication efficacy.;Inclusion criteria: 1. Aged 18 to 70 years old, men and women are not limited; 2. Due to abdominal pain, bloating, acid reflux, belching, nausea, vomiting, heartburn, chest pain, black and so on discomfort symptoms of HP-related diseases; 3. Antibiotics, bismuth, H2 receptor antagonists, or PPI are not used in the last two weeks; 4. Urine breath test was positive; 5. Agreed to endoscopy to take gastric mucosal biopsy specimens were HP culture and drug sensitivity test; 6. Agreed to follow the initial treatment of HP eradication therapy and are willing to follow the doctor's follow-up survey of eradication efficacy.;Inclusion criteria: 1. Aged 18 to 70 years old, men and women are not limited; 2. Due to abdominal pain, bloating, acid reflux, belching, nausea, vomiting, heartburn, chest pain, black and so on discomfort symptoms of HP-related diseases; 3. Antibiotics, bismuth, H2 receptor antagonists, or PPI are not used in the last two weeks; 4. Urine breath test was positive; 5. Agreed to endoscopy to take gastric mucosal biopsy specimens were HP culture and drug sensitivity test; 6. Agreed to follow the initial treatment of HP eradication therapy and are willing to follow the doctor's follow-up survey of eradication efficacy.;Inclusion criteria: 1. Aged 18 to 70 years old, men and women are not limited; 2. Due to abdominal pain, bloating, acid reflux, belching, nausea, vomiting, heartburn, chest pain, black and so on discomfort symptoms of HP-related diseases; 3. Antibiotics, bismuth, H2 receptor antagonists, or PPI are not used in the last two weeks; 4. Urine breath test was positive; 5. Agreed to endoscopy to take gastric mucosal biopsy specimens were HP culture and drug sensitivity test; 6. Agreed to follow the initial treatment of HP eradication therapy and are willing to follow the doctor's follow-up survey of eradication efficacy.;Inclusion criteria: 1. Aged 18 to 70 years old, men and women are not limited; 2. Due to abdominal pain, bloating, acid reflux, belching, nausea, vomiting, heartburn, chest pain, black and so on discomfort symptoms of HP-related diseases; 3. Antibiotics, bismuth, H2 receptor antagonists, or PPI are not used in the last two weeks; 4. Urine breath test was positive; 5. Agreed to endoscopy to take gastric mucosal biopsy specimens were HP culture and drug sensitivity test; 6. Agreed to follow the initial treatment of HP eradication therapy and are willing to follow the doctor's follow-up survey of eradication efficacy.

Exclusion criteria

Exclusion criteria: 1. Serious heart, liver, kidney damage; 2. Pregnant or lactating women; 3. Patients with other adverse effects such as severe liver disease, heart disease, kidney disease, malignancy and alcoholism, bleeding, perforation, pyloric obstruction, and cancer complications; 4. There are esophagus, gastrointestinal surgery history; 5. Participate in other drug studies within 3 months of the study drug; 6. Patients can not correctly express their complaints, such as mental illness, severe neurosis; 7. Patients with gastric mucosal biopsy contraindications (coagulation disorders, taking anticoagulants, etc.); 8. Patients taking non-steroidal anti-inflammatory drugs or alcohol at the same time; 9. Patients with HP drug susceptibility test antibiotics for any drug allergy.;Exclusion criteria: 1. Serious heart, liver, kidney damage; 2. Pregnant or lactating women; 3. Patients with other adverse effects such as severe liver disease, heart disease, kidney disease, malignancy and alcoholism, bleeding, perforation, pyloric obstruction, and cancer complications; 4. There are esophagus, gastrointestinal surgery history; 5. Participate in other drug studies within 3 months of the study drug; 6. Patients can not correctly express their complaints, such as mental illness, severe neurosis; 7. Patients with gastric mucosal biopsy contraindications (coagulation disorders, taking anticoagulants, etc.); 8. Patients taking non-steroidal anti-inflammatory drugs or alcohol at the same time; 9. Patients with HP drug susceptibility test antibiotics for any drug allergy.;Exclusion criteria: 1. Serious heart, liver, kidney damage; 2. Pregnant or lactating women; 3. Patients with other adverse effects such as severe liver disease, heart disease, kidney disease, malignancy and alcoholism, bleeding, perforation, pyloric obstruction, and cancer complications; 4. There are esophagus, gastrointestinal surgery history; 5. Participate in other drug studies within 3 months of the study drug; 6. Patients can not correctly express their complaints, such as mental illness, severe neurosis; 7. Patients with gastric mucosal biopsy contraindications (coagulation disorders, taking anticoagulants, etc.); 8. Patients taking non-steroidal anti-inflammatory drugs or alcohol at the same time; 9. Patients with HP drug susceptibility test antibiotics for any drug allergy.;Exclusion criteria: 1. Serious heart, liver, kidney damage; 2. Pregnant or lactating women; 3. Patients with other adverse effects such as severe liver disease, heart disease, kidney disease, malignancy and alcoholism, bleeding, perforation, pyloric obstruction, and cancer complications; 4. There are esophagus, gastrointestinal surgery history; 5. Participate in other drug studies within 3 months of the study drug; 6. Patients can not correctly express their complaints, such as mental illness, severe neurosis; 7. Patients with gastric mucosal biopsy contraindications (coagulation disorders, taking anticoagulants, etc.); 8. Patients taking non-steroidal anti-inflammatory drugs or alcohol at the same time; 9. Patients with HP drug susceptibility test antibiotics for any drug allergy.;Exclusion criteria: 1. Serious heart, liver, kidney damage; 2. Pregnant or lactating women; 3. Patients with other adverse effects such as severe liver disease, heart disease, kidney disease, malignancy and alcoholism, bleeding, perforation, pyloric obstruction, and cancer complications; 4. There are esophagus, gastrointestinal surgery history; 5. Participate in other drug studies within 3 months of the study drug; 6. Patients can not correctly express their complaints, such as mental illness, severe neurosis; 7. Patients with gastric mucosal biopsy contraindications (coagulation disorders, taking anticoagulants, etc.); 8. Patients taking non-steroidal anti-inflammatory drugs or alcohol at the same time; 9. Patients with HP drug susceptibility test antibiotics for any drug allergy.

Design outcomes

Primary

MeasureTime frame
HP eradication rate;

Countries

China

Contacts

Public ContactJieming Shi;Jieming Shi;Jieming Shi;Jieming Shi;Jieming Shi ;;;;

Huzhou Central Hospital;Huzhou Central Hospital;Huzhou Central Hospital;Huzhou Central Hospital;Huzhou Central Hospital

hzsjmin@126.com;hzsjmin@126.com;hzsjmin@126.com;hzsjmin@126.com;hzsjmin@126.com+86 13857270258;+86 13857270258;+86 13857270258;+86 13857270258;+86 13857270258

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026