asthma
Conditions
Interventions
Asthma children:no intervention
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Age
No minimum to 14 Years
Inclusion criteria
Inclusion criteria: 1. mild to moderate persistent asthma that meet the 2008 diagnostic criteria established by Chinese Medical Association Respiratory Diseases Asthma Study Group; 2. Aged 0-14 years old, male or female; 3. Bronchial provocation test or Bronchodilation test positive; 4. No use of systemic or inhaled corticosteroids during the last 4 weeks; 5. No use of leukotriene receptor modulators, theophylline derivatives andmast cell stabilizers Within 2 weeks before the test; 6. No use of long-acting ß2 agonists, oral ß2 agonists or inhaled anti- cholinergic receptor 1 week before the test; 7. Abscent of without respiratory infections andsystemic infections, particularly acute respiratory infections , tuberculosis, fungal infections 4 weeks before the test; 8. Abscent of acute asthma exacerbations andhospitalizations 4 weeks before the test; 9. Did not receive any study medication 4 weeks before the test; 10. No inhaled corticosteroids, ß2 agonists allergies; 11. No serious heart, liver, kidney andother systemic disorders; 12. Agreed to join the study andsigned a written informed consent.;Inclusion criteria: 1. mild to moderate persistent asthma that meet the 2008 diagnostic criteria established by Chinese Medical Association Respiratory Diseases Asthma Study Group; 2. Aged 0-14 years old, male or female; 3. Bronchial provocation test or Bronchodilation test positive; 4. No use of systemic or inhaled corticosteroids during the last 4 weeks; 5. No use of leukotriene receptor modulators, theophylline derivatives andmast cell stabilizers Within 2 weeks before the test; 6. No use of long-acting ß2 agonists, oral ß2 agonists or inhaled anti- cholinergic receptor 1 week before the test; 7. Abscent of without respiratory infections andsystemic infections, particularly acute respiratory infections , tuberculosis, fungal infections 4 weeks before the test; 8. Abscent of acute asthma exacerbations andhospitalizations 4 weeks before the test; 9. Did not receive any study medication 4 weeks before the test; 10. No inhaled corticosteroids, ß2 agonists allergies; 11. No serious heart, liver, kidney andother systemic disorders; 12. Agreed to join the study andsigned a written informed consent.;Inclusion criteria: 1. mild to moderate persistent asthma that meet the 2008 diagnostic criteria established by Chinese Medical Association Respiratory Diseases Asthma Study Group; 2. Aged 0-14 years old, male or female; 3. Bronchial provocation test or Bronchodilation test positive; 4. No use of systemic or inhaled corticosteroids during the last 4 weeks; 5. No use of leukotriene receptor modulators, theophylline derivatives andmast cell stabilizers Within 2 weeks before the test; 6. No use of long-acting ß2 agonists, oral ß2 agonists or inhaled anti- cholinergic receptor 1 week before the test; 7. Abscent of without respiratory infections andsystemic infections, particularly acute respiratory infections , tuberculosis, fungal infections 4 weeks before the test; 8. Abscent of acute asthma exacerbations andhospitalizations 4 weeks before the test; 9. Did not receive any study medication 4 weeks before the test; 10. No inhaled corticosteroids, ß2 agonists allergies; 11. No serious heart, liver, kidney andother systemic disorders; 12. Agreed to join the study andsigned a written informed consent.;Inclusion criteria: 1. mild to moderate persistent asthma that meet the 2008 diagnostic criteria established by Chinese Medical Association Respiratory Diseases Asthma Study Group; 2. Aged 0-14 years old, male or female; 3. Bronchial provocation test or Bronchodilation test positive; 4. No use of systemic or inhaled corticosteroids during the last 4 weeks; 5. No use of leukotriene receptor modulators, theophylline derivatives andmast cell stabilizers Within 2 weeks before the test; 6. No use of long-acting ß2 agonists, oral ß2 agonists or inhaled anti- cholinergic receptor 1 week before the test; 7. Abscent of without respiratory infections andsystemic infections, particularly acute respiratory infections , tuberculosis, fungal infections 4 weeks before the test; 8. Abscent of acute asthma exacerbations andhospitalizations 4 weeks before the test; 9. Did not receive any study medication 4 weeks before the test; 10. No inhaled corticosteroids, ß2 agonists allergies; 11. No serious heart, liver, kidney andother systemic disorders; 12. Agreed to join the study andsigned a written informed consent.;Inclusion criteria: 1. mild to moderate persistent asthma that meet the 2008 diagnostic criteria established by Chinese Medical Association Respiratory Diseases Asthma Study Group; 2. Aged 0-14 years old, male or female; 3. Bronchial provocation test or Bronchodilation test positive; 4. No use of systemic or inhaled corticosteroids during the last 4 weeks; 5. No use of leukotriene receptor modulators, theophylline derivatives andmast cell stabilizers Within 2 weeks before the test; 6. No use of long-acting ß2 agonists, oral ß2 agonists or inhaled anti- cholinergic receptor 1 week before the test; 7. Abscent of without respiratory infections andsystemic infections, particularly acute respiratory infections , tuberculosis, fungal infections 4 weeks before the test; 8. Abscent of acute asthma exacerbations andhospitalizations 4 weeks before the test; 9. Did not receive any study medication 4 weeks before the test; 10. No inhaled corticosteroids, ß2 agonists allergies; 11. No serious heart, liver, kidney andother systemic disorders; 12. Agreed to join the study andsigned a written informed consent.
Exclusion criteria
Exclusion criteria: 1. There are other hereditary diseases in the 3-generation immediate family members; 2. Unable or unwilling to comply with research operations or study visits; 3. There are one of the following diseases: (1) congenital airway, pulmonary parenchymal dysplasia; (2) bronchial dilatation patients; (3) airway obstruction or external pressure; (4) active tuberculosis patients; (5) congenital heart disease patients.;Exclusion criteria: 1. There are other hereditary diseases in the 3-generation immediate family members; 2. Unable or unwilling to comply with research operations or study visits; 3. There are one of the following diseases: (1) congenital airway, pulmonary parenchymal dysplasia; (2) bronchial dilatation patients; (3) airway obstruction or external pressure; (4) active tuberculosis patients; (5) congenital heart disease patients.;Exclusion criteria: 1. There are other hereditary diseases in the 3-generation immediate family members; 2. Unable or unwilling to comply with research operations or study visits; 3. There are one of the following diseases: (1) congenital airway, pulmonary parenchymal dysplasia; (2) bronchial dilatation patients; (3) airway obstruction or external pressure; (4) active tuberculosis patients; (5) congenital heart disease patients.;Exclusion criteria: 1. There are other hereditary diseases in the 3-generation immediate family members; 2. Unable or unwilling to comply with research operations or study visits; 3. There are one of the following diseases: (1) congenital airway, pulmonary parenchymal dysplasia; (2) bronchial dilatation patients; (3) airway obstruction or external pressure; (4) active tuberculosis patients; (5) congenital heart disease patients.;Exclusion criteria: 1. There are other hereditary diseases in the 3-generation immediate family members; 2. Unable or unwilling to comply with research operations or study visits; 3. There are one of the following diseases: (1) congenital airway, pulmonary parenchymal dysplasia; (2) bronchial dilatation patients; (3) airway obstruction or external pressure; (4) active tuberculosis patients; (5) congenital heart disease patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| STIP1 gene;GLCCI1 gene;forced pulmonary function test;blood routine examination;IgE;allergen; | — |
Countries
China
Contacts
Public ContactXiangrong Zheng;Xiangrong Zheng;Xiangrong Zheng;Xiangrong Zheng;Xiangrong Zheng ;;;;
Central South University Xiangya Hospital;Central South University Xiangya Hospital;Central South University Xiangya Hospital;Central South University Xiangya Hospital;Central South University Xiangya Hospital
Outcome results
None listed