depression
Conditions
Interventions
liver qi stagnation group:xiaoyaosan
kidney qi deficiency group:Jinkuishenqiwan
fluoxetine group:fluoxetine
normal control group:none
Sponsors
Beijing University of Chinese Medicine 3rd Affiliated Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: The normal control group: 1) right-handedness; 2) aged 18-45 years; 3) absence of a primary neurological illness; 4) absence of history of any other major psychiatric diseases; 5) absence of a medical illness that could impair cognitive function; 6) absence of any brain white matter changes in T2-weigheted magnetic resonance images; 7) no metallic foreign bodies, pacemakers, metallic dentures, or amalgam fillings; 8) HAMD score=17 and <24 and Young manic rating scale scores<5; 3) no diagnosis for any other mental disorders according to DISM-IV criteria; 4) medication-free for at least 2 weeks. TCM syndromes group: the patients are diagnoised by 2 senior internal medicine of TCM according to Guidelines for diagnosis and treatment of common internal disease of Chinese medicine: depression part, which was edited by China association of TCM, and supplemented with diagnostic critera of liver qi stagnation and kidney qi deficiency which was developed by China society of integrated traditional and western medicine in 1986.
Exclusion criteria
Exclusion criteria: The control and depressive group: 1) secondary physical diseases; 2) vital life signs was unstable; 3) seriously aphasia and agnosia and unable to communicate; 4) 24-item Hamilton Depression Rating scale(HAMD)scores >24; 5) excessive drinking and drug addict; 6) none depressive psychosis diagnosed by modern medicine; 7) seriously suicidal tendency(the third item of HAMD scores>3); 8) abnormal biochemical index; 9) woman in incubation and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| biomarker;blood oxygenation level dependent; | — |
Countries
China
Contacts
Public ContactMiao Qu
Xuanwu Hospital of Captial Medicial University
Outcome results
None listed