postoperative delirium
Conditions
Interventions
2:None
Sponsors
Affiliated Drum Tower Hospital of Medical School of Nanjing University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective non-cardiac surgery under general anesthesia; 2. Aged 65 years or older patients and aged 20-30 years young patients; 3. ASA I-III; 4. Patients who have signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe organ dysfunction; 2. Mental or neurological disorders such as schizophrenia, epilepsy, Parkinson's disease, or Alzheimer's disease; 3. Patients with recent brain injury, cerebral infarction, cerebral hemorrhage; 4. Patients with severe hearing, visual, or language disorders that cannot cooperate; 5. Patients with history of drug abuse or dependence; 6. Patients with history of alcoholism; 7. Patients with low literacy and simple Intelligence Scale (MMSE) < 23 points.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Delirium scale score;Postoperative pain score;Mini-mental State Examinatlon score;RASS sedation score;blood pressure;heart rate;Perioperative medication;Sleep quality score;Mitochondrial DNA methylation level;Mitochondrial DNA hydroxymethylation level; | — |
Countries
China
Contacts
Public ContactSong Fen
Affiliated Drum Tower Hospital of Medical School of Nanjing University
Outcome results
None listed