Thyroid carcinoma
Conditions
Interventions
Cross-section group:Take LT4
Longitudinal study:surgery
LT4 absorb groups:LT4 absorb
Sponsors
The First Affiliated Hospital of Harbin Medical Universtiy
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18 years to 65 years, male and female; (2) Clinically diagnosed as Hashimoto's thyroiditis; (3) Clinical staging for thyroid function in normal period.
Exclusion criteria
Exclusion criteria: (1) Three months using a variety of antibiotics, prebiotics, probiotics or lactic acid products etc.; (2) With a history of over 2 years of alcohol abuse; (3) Pregnancy or lactation; (4) Oral, respiratory and gastrointestinal diseases; (5) With a variety of metabolic diseases, such as hyperthyroidism, hypothyroidism, obesity, hypertension, diabetes, gallstones, liver diseases etc.; (6) With other autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease etc.; (7) History of gastrointestinal surgery, or other recent surgical history; (8) Family history, history of mental illness, etc.; (9) The subjects are participating in other research projects; (10) The researchers believe that other reasons are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Flora diversity;Abundance of flora;Thyroglobulin antibody; Thyroid peroxidase antibody;Classification of lymphocyte subsets;Immune associated molecules;Metabolomics; | — |
Countries
China
Contacts
Public ContactYunwei Wei
The First Affiliated Hospital of Harbin Medical Universtiy
Outcome results
None listed