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Effects of exogenous thyroid hormone on the intestinal microflora of host

Effects of exogenous thyroid hormone on the intestinal microflora of host

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17012763
Enrollment
Unknown
Registered
2017-09-21
Start date
2017-09-21
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid carcinoma

Interventions

Take exogenous thyroid hormone group:Take exogenous thyroid hormone

Sponsors

The First Affiliated Hospital of Harbin Medical Universtiy
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 years to 65 years, male and female; 2. Pathological diagnosis of differentiated thyroid carcinoma; 3. Thyroid complete resection; 4. Thyroid function has reached the normal range.

Exclusion criteria

Exclusion criteria: (1) Three months using a variety of antibiotics, prebiotics, probiotics or lactic acid products etc.; (2) With a history of over 2 years of alcohol abuse; (3) Pregnancy or lactation; (4) Oral, respiratory and gastrointestinal diseases; (5) With a variety of metabolic diseases, such as hyperthyroidism, hypothyroidism, obesity, hypertension, diabetes, gallstones, liver diseases etc.; (6) With other autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease etc.; (7) History of gastrointestinal surgery, or other recent surgical history; (8) Family history, history of mental illness, etc.; (9) The subjects are participating in other research projects; (10) The researchers believe that other reasons are not suitable for clinical trials; (11) The medicine brand was challenged in the preserved phasee.

Design outcomes

Primary

MeasureTime frame
Flora diversity;Abundance of flora;Thyroglobulin antibody;Thyroid peroxidase antibody;Classification of lymphocyte subsets; Immune associated molecules;Metabolomics;Triglyceride;Cholesterol;

Countries

China

Contacts

Public ContactYunwei Wei

The First Affiliated Hospital of Harbin Medical Universtiy

hydwyw11@hotmail.com+86 0451-85555730

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026