acute coronary syndrome
Conditions
Interventions
clopidogrel-resistance:Determination of the platelet accumulation rate and Genotyping
not clopidogrel-resistance:Determination of the platelet
Sponsors
Central Hospital of Nanchong, The Second Clinical School of North Sichuan Medical College
Eligibility
Sex/Gender
All
Age
38 Years to 70 Years
Inclusion criteria
Inclusion criteria: The patients (aged 18-75 years old) treated at the Department of Cardiovascular Medicine, Nanchong Central Hospital were included in the study. They were diagnosed as ACS by clinical manifestations, electrocardiogram (ECG), cardiac enzyme test or coronary angiography. All study procedures were conducted in accordance with the Helsinki Declaration of 1975 and were approved by the Nanchong Central Hospital Institutional Review Board
Exclusion criteria
Exclusion criteria: 1) allergy to clopidogrel; 2) having taken aspirin or clopidogrel or other antiplatelet drugs within 7 days prior to the study; 3) platelet count >300x10^9/L or <100x10^9/L; 4) abnormal liver and kidney functions (ALT or AST level higher by 3 times above the upper limit of normal range; GFR<60ml/min); 5) active peptic ulcer; 6) having received major surgeries, cerebrovascular accidents or history of hemorrhage recently.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the platelet accumulation rate;Association analysis;Logistic regression analysis on potential risk factors for CR; | — |
Countries
China
Contacts
Public ContactQiang Su
Central Hospital of Nanchong, The Second Clinical School of North Sichuan Medical College
Outcome results
None listed