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The single nucleotide polymorphism G-201A in the Promoter of CXCL-10 Gene is an important factor in the occurrence of occult chronic HCV infection

The single nucleotide polymorphism G-201A in the Promoter of CXCL-10 Gene is an important factor in the occurrence of occult chronic HCV infection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17011802
Enrollment
Unknown
Registered
2017-06-29
Start date
2011-01-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Hepatitis C Virus

Interventions

occult HCV infection group:N/A
control group:N/A

Sponsors

China-Japan Union Hospital of Jilin University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with both anti-HCV and serum HCV RNA quantitative negative, but HCV RNA positive in liver tissue.

Exclusion criteria

Exclusion criteria: 1. Patients with occult hepatitis B virus infection,non-alcoholic steatohepatitis,alcoholic liver disease,drug-induced liver disease,autoimmune liver disease,genetic metabolic liver disease; 2. Patients with other types of hepatitis virus infection and EBV, CMV, HIV infection; 3. HCV infection patients with decompensated cirrhosis,primary liver cancer; 4. Patients with severe heart,brain or kidney disease; 5. HCV infection patients who are receiving or previous received interferon or interferon combined with ribavirin antiviral treatment.

Design outcomes

Primary

MeasureTime frame
the single nucleotide polymorphism G-201A in the Promoter of CXCL-10 Gene;serum CXCL-10 level;liver tissue CXCL-10 expression;liver tissue HAI score;liver tissue Ishak score;—

Countries

China

Contacts

Public ContactJiangbin Wang

China-Japan Union Hospital of Jilin University

zrlwangjb@medmail.com.cn+86 13578993125

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026