Type 2 Diabetes
Conditions
Interventions
T2DM subjects with macroangiopathy:Nil
T2DM subjects without macroangiopathy:Nil
Normal Contro:Nil
Sponsors
Affiliated Longyan First Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria for the subjects with T2DM using World Health Organization criteria(1999) and/or was being treated with insulin or oral hypoglycemic agents.Inclusion criteria for the diabetic macroangiopathy applied were at least one of the following: diagnosis of coronary heart disease, cerebral infarction and peripheral vascular ischemic disease by the medical specialist ever accoding to the clinical symptoms, signs and auxiliary examination definitely, cerebral infarction lesions were found by brain magnetic resonance imaging scan, atherosclerotic plaques of peripheral blood vessels (bilateral carotid artery or lower extremity artery, etc)were found by color doppler ultrasound examination, ischemic myocardial injury was found by ECG, dynamic electrocardiogram, echocardiography, percutaneous coronary angiography.
Exclusion criteria
Exclusion criteria: Exclusion criteria applied were as follows: acute infectious disease such as cold or diarrhea, uncontrolled hypertension, non homeostasis such as diabetic ketoacidosis, hyperosmolar syndrome or hypoglycemia, severe dyslipidemia, clear microvascular lesions such as diabetic nephropathy or retinopathy, autoimmune disease or maligant tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adiponectin;intima media thickness of dorsalis pedis artery (D-IMT); | — |
Secondary
| Measure | Time frame |
|---|---|
| body mass index;systolic blood pressure;diastolic blood pressure;fasting plasma glucose;postprandial 2 hours blood glucose;glycosylated hemoglobin;total cholesterol;triglyceride;high density lipoprotein cholesterol;low density lipoprotein cholesterol;uric acid;Fibrinogen;fasting insulin;homeostasis model assessment 2 of insulin resistance(HOMA2);high sensitivity C reactive protein;Diabetic duration;Age;gender;Cigarette smoking;Alcohol drinking; | — |
Countries
China
Contacts
Public ContactMei Tu
Affiliated Longyan First Hospital of Fujian Medical University
Outcome results
None listed