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Relationship between genetic polymorphism and susceptibility to trimethylaminuria

Relationship between genetic polymorphism and susceptibility to trimethylaminuria

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17011595
Enrollment
Unknown
Registered
2017-06-09
Start date
2017-06-30
Completion date
Unknown
Last updated
2017-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

trimethylaminuria

Interventions

Case and Control:Nil

Sponsors

Department of Clinical Pharmacology, Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. subjects self-reporting accord with urinary symptoms of trimethylamine; 2. participants whose trimethylamine oxide/total trimethylamine ratio < 90% in the urine; 3. weight greater than 50 kg, subjects body mass index (BMI) of between 19 ~ 25 kg/m2, with a group of subjects weight difference within 10% of the average weight; 4. subjects volunteer for the experiment and is willing to test in accordance with the provisions of this test procedure; 5. signed informed consent.

Exclusion criteria

Exclusion criteria: 1. menstrual period women; 2. two months before the experiment taking antibiotics; 3. has a history of drug abuse; 4. urinary tract or vaginal bacterial infections; 5. remove osmidrosis patients.

Design outcomes

Primary

MeasureTime frame
trimethylamine oxide/total trimethylamine ratio in urine;

Countries

China

Contacts

Public ContactWei Zhang

Department of Clinical Pharmacology, Xiangya Hospital, Central South University

yjsd2003@163.com+86 0731-84805380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026