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Correlation analysis between perinatal prognosis of gestational hypertension disease and maldevelopment of the nervous system in childhood

Correlation analysis between perinatal prognosis of gestational hypertension disease and maldevelopment of the nervous system in childhood

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17011411
Enrollment
Unknown
Registered
2017-05-16
Start date
2017-05-03
Completion date
Unknown
Last updated
2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

(hypertensive disorders in pregnancy

Interventions

Case series:Nil

Sponsors

Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women who are diagnosed with hypertension after 28 weeks of pregnancyClassification is as follows: 1. Gestational hypertension: high blood pressure during pregnancy, systolic blood pressure =140mmHg and (or) diastolic blood pressure = 90mmHg Urine protein (-); 2. Preeclampsia: mild for systolic blood pressure after 20 weeks of gestation ? 140 MMHG and (or) diastolic ? 90 MMHG, associated with proteinuria ? 0.3 g / 24 hours, or random urine protein (+); The high blood pressure and urinary protein continued to rise, and the maternal organs were not fully functional or the complications of the fetus (the eighth edition of the women's obstetrics science) 7; 3. Eclampsia: a convulsion that cannot be explained by other causes on the basis of eclampsia; 4. Preeclampsia of chronic hypertension: no albuminuria before pregnancy, and proteinuria after pregnancy, 30 g/24 hours after pregnancy; Proteinuria before or after pregnancy, a significant increase in proteinuria after pregnancy or a further increase in blood pressure or thrombocytopenia (100 by 10*9/L); 5. Pregnancy with chronic hypertension systolic blood pressure before 20 gestational weeks ? 140 MMHG and (or) diastolic ? 90 MMHG (with the exception of trophocyte diseases), no obvious increase during pregnancy; The first diagnosis of high blood pressure after 20 weeks is followed by 12 weeks postpartum.

Exclusion criteria

Exclusion criteria: 1. A patient with a family history of nervous system development; 2. Twin pregnancy; 3. Fetal abnormalities; 4. fetal chromosome abnormalities confirmed by Prenatal diagnosis; 5. The combination of other obstetric complications and complications (such as gestational diabetes during pregnancy, and intrahepatic bile deposition during pregnancy); 6. Intrauterine infection; 7. Complications of birth (such as cord prolapse, prenatal acute loss of blood); 8. The diagnosis of hypertension is excluded after 3 months of postpartum; 9. Giving up the fetus to terminate the pregnancy.

Design outcomes

Primary

MeasureTime frame
infant development;

Contacts

Public ContactJin Jin

Southern Hospital, Southern Medical University

luckyjinj@163.com+86 13710531065

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026