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The expression of cytokines IFN-?, IL-4, IL-17A, TGF-ß1 in peripheral blood and follicular fluid of patients testing positive for anti-thyroid autoantibodies and its influence on IVF-ET pregnancy outcomes

The expression of cytokines IFN-?, IL-4, IL-17A, TGF-ß1 in peripheral blood and follicular fluid of patients testing positive for anti-thyroid autoantibodies and its influence on IVF-ET pregnancy outcomes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-ROC-17011396
Enrollment
Unknown
Registered
2017-05-13
Start date
2016-08-07
Completion date
Unknown
Last updated
2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anti-thyroid autoantibody

Interventions

Case series:Nil

Sponsors

Yantai Yuhuangding Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: (1) basic FSH value<10 IU/L on the third day of menstrual cycle; (2) infertility due to male partner, oviduct or both; (3) patient has no other autoimmune disease; (4) normal superovulation, that is 3 or more follicles of which the measured values are =18 mm at the end of superovulation cycle; (5) thyroid gland function [Thyrotropin(TSH), Free Thyroxine (FT4), Free Triiodothyronine (FT3)] are in normal range, and there is no history of thyroid disease and medication.

Exclusion criteria

Exclusion criteria: patients with polycystic ovary syndrome and endometriosis excluded

Design outcomes

Primary

MeasureTime frame
implantation rate;pregnancy rate;early miscarriage rate;—

Countries

China

Contacts

Public ContactCuifang Hao

Department of Reproductive Medicine, Yantai Yuhuangding Hospital, Affiliated Hospital of Qingdao University

cuifanghao@aliyun.com+86 13863859669

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026