sepsis
Conditions
Interventions
bacterial infection:none
mixed infection:none
fungal infection:none
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Enrolled patients should be older than 18 years of age with confirmed or presumed infection, that they met two or more criteria for systemic inflammatory response syndrome and that there was evidence of refractory hypotension or serum lactate greater than 2 mmol per liter. Refractory hypotension was defined as systolic blood pressure below 90 mm Hg or mean arterial pressure (MAP) below 65 mm Hg after an intravenous fluid challenge of 30 ml or more per kilogram of body weight. All the patients will be from ICU of Peking Union Medical College Hospital.
Exclusion criteria
Exclusion criteria: age younger than 18 years, pregnancy, or giving up on treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T-bet;Eomes;Granzyme B;Perforin;IFN;IL-2;IL-6;IL-7;IL-12;mTOR;S6K; | — |
Countries
China
Contacts
Public ContactCui Na
Department of Critical Care Medicine, Peking Union Medical College Hospital
Outcome results
None listed